Maternal serum markers in second-trimester oligohydramnios

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Maternal serum markers in second-trimester oligohydramnios.

The levels of the maternal serum markers alpha-fetoprotein (AFP), human chorionic gonadotrophin (hCG), and unconjugated oestriol (uE3) in 35 pregnant women with early second-trimester oligohydramnios differed from those in a reference population of 1699 singleton pregnancies. Maternal serum AFP levels above the 95th centile of the population distribution were observed in 80 per cent (16/20) of ...

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Maternal serum alpha-fetoprotein levels and fetal outcome in early second-trimester oligohydramnios.

Early second-trimester oligohydramnios was associated with normal maternal serum alpha-fetoprotein (MSAFP) levels in nine out of 26 cases (35 per cent). Congenital malformations of the fetal urinary tract resulting in fetal anuria were present in nine cases; in seven of them, normal MSAFP levels were measured. In contrast, normal MSAFP levels were established in only 2 out of the 17 cases witho...

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Oligohydramnios during the Early Second Trimester

Oligohydramnios developing early in pregnancy is less common, and the fetal outcomes are usually poor. This is because prolonged decrease in amniotic fluid may cause compression sequences, such as pulmonary hypoplasia, muscle hypotrophy or joint constriction. Early-onset oligohydramnios may be caused by preterm premature rupture of membranes (pPROM) or decreased secretion of amniotic fluid. Ear...

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Second-trimester uterine artery Doppler pulsatility index and maternal serum PP13 as markers of pre-eclampsia.

OBJECTIVE To evaluate whether measurement of maternal serum PP13 at 22 to 24 weeks of gestation, alone or in combination with second-trimester biochemical markers or uterine artery pulsatility measured by Doppler velocimetry, is useful in predicting those women at risk of developing pre-eclampsia. STUDY DESIGN A nested case-control study of pre-eclampsia cases with controls matched for gestat...

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Relationship between Maternal Serum Biomarkers (HCG, AFP, UE3, and Inhibin A) in the Second Trimester of Pregnancy and Preterm Labor

Aims: Preterm labor (PTL) is one of the most important medical community problems and the main cause of infant morbidity and mortality after congenital anomalies. Several studies have shown a significant association between the abnormal levels of quadruple test with PTL. However, there is no general agreement on the value of quadruple tests for predicting complications among studies. This study...

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ژورنال

عنوان ژورنال: Prenatal Diagnosis

سال: 1994

ISSN: 0197-3851,1097-0223

DOI: 10.1002/pd.1970140709